Author (Year) Reference Language ICD 10 (disease) Design Cases (
) Randomization Blinding Groups (
) Intervention Control Kampo treatment Sasaki et al. (2006) [82 ] J C18.9 (gastroenteric cancer) RCT 168 No No 2 SK S, K juzentaihoto Sasaki et al. (2007) [83 ] J C18.9 (cancer chemotherapy) RCT 168 No No 2 SK S, K juzentaihoto Adachi (1988) [84 ] J C50.9 (advanced breast cancer) RCT 74 E No 2 SK S juzentaihoto Yamamoto et al. (2003) [85 ] J D25.9 (uterine adenomyosis) RCT 24 R No 2 SK S keishibukuryogan Akase et al. (2003) [86 ] J D50.0 (anemia due to uterine myoma) RCT 25 R No 2 K S tokishakuyakusan Aoe (2007) [87 ] J D50.8 (iron deficiency anemia) RCT 120 R No 3 SK S juzentaihoto Yanagibori et al. (1995) [88 ] J D50.9 (Iron deficiency anemia,) RCT 39 E SB 2 SK S ninjinyoeito Aoe et al. (2000) [89 ] J D62 (acute posthaemorrhagic anemia) RCT 57 R No 2 SK S juzentaihoto Aoe et al. (1999) [90 ] J D62 (acute posthaemorrhagic anemia) RCT 90 R No 3 SK S juzentaihoto, ninjinyoeito Azuma et al. (1994) [91 ] J E10-E14 (non-insulin-dependent diabetes mellitus) RCT 18 E No 2 SK S seishinrenshiin Yamano et al. (1995) [92 ] J E78.5 (hyperlipidaemia) RCT 92 E No 3 SK S, NT daisaikoto Sasaki et al. (1991) [93 ] J E78.5 (hyperlipidaemia) RCT 40 R No 3 SK S daisaikoto Ishida et al. (1999) [94 ] J F41.9 (anxiety disorder, unspecified) RCT 15 R No 2 SK S saibokuto Yamagiwa and Fujita (2007) [95 ] J F45.3 (abnomal sensation) quasi-RCT 86 R No 2 K S rikkunshito Maruyama (2006) [96 ] J G43.9 (migraine, unspecified) RCT-cross over 28 R No 2 K S goshuyuto Kimura et al. (1991) [97 ] J G51.3 (facial spasm) RCT 20 R No 2 SK S shakuyakukanzoto Sekine et al. (2003) [98 ] J G54.4 (lumbosacral root disorders) RCT-cross over 20 R No 2 K S goshajinkigan Inoue (2001) [99 ] J H65.0 (acute serous otitis media) Case Control 34 No No 2 K S shoseiryuto, eppikajutsuto
Matsushita et al. (1995) [100 ] J I67.9, I67.8, I10 (cerebrovascular disease, hypertension) RCT 22 E No 2 K S chotosn Akiyama et al. (2001) [101 ] J I73.0 (raynaud's syndrome) Case Control 49 No No 2 SK S tokishakuyakusan, orengedokuto Fujimori et al. (2001) [102 ] J J00 (postinfections cough) RCT 25 R No 2 K S bakumondoto Kimoto and Kuroki (2005) [103 ] J J10 (influenza) Case Control 19 No No 2 SK S maoto Kubo et al. (2007) [104 ] E J10.1 (type A influenza infection) quasi-RCT 37 No No 2 SK S maoto Kato et al. (2005) [105 ] J J44.9 (chronic obstructive pulmonary disease) RCT 31 E No 2 SK S seihaito Tatsumi et al. (2009) [106 ] E J44.9 (chronic obstructive pulmonary disease) RCT 71 E No 2 K S hochuekkito Nishizawa et al. (2004) [107 ] J J45.0 (bronchial asthma) RCT 161 R No 2 K S shinbito inhalation Nishizawa et al. (2003) [108 ] J J45.0 (bronchial asthma) RCT 114 R No 2 K S shinbito inhalation Nishizawa et al. (2002) [109 ] J J45.0 (bronchial asthma) RCT 107 R No 2 K S saibokuto Nishizawa et al. (2002) [110 ] J J45.0 (bronchial asthma) RCT 94 R No 2 K S saibokuto inhalation Egashira and Nagano (1993) [111 ] E J45.9 (bronchial asthma) RCT 112 E SB 2 SK S saibokuto Mikamo et al. (2007) [112 ] J J98.9 (respiratory infection) RCT 116 No No 3 SK S jumihaidokuto, kakkoto, keishito, kososan, shosaikoto, hochuekkito Umemoto et al. (2007) [113 ] J K11.7 (dry mouth) RCT 100 No No 3 K S bakumondoto Yamada et al. (1998) [114 ] J K14.6 (glossodynia) RCT 104 R No 2 K S saibokuto Kato et al. (2005) [115 ] J K21.0 (gastro-oesophageal reflux disease with oesophagitis) RCT 19 E No 2 SK S hangekobokuto Koide (2006) [116 ] J K21.9 (gastro-oesophageal reflux disease without oesophagitis) RCT 118 No No 3 SK, K S, K rikkunshito Higuchi et al. (1999) [117 ] E K26.9 (Helicobacter pylori) RCT 63 R No 2 SK S goshuyuto Yamaguchi and Koide (2007) [118 ] J K30 (dyspepsia) RCT 120 E No 3 K S rikkunshito Nishizawa et al. (2004) [119 ] J K59.0 (constipation) RCT 318 R No 2 SK S kumibinroto Nakajima et al. (2003) [120 ] J K73.9 (chronic hepatitis) RCT 100 E No 3 K S, K shosaikoto Nakajima et al. (1999) [121 ] J K73.9 (chronic hepatitis) RCT 99 R No 2 SK S shosaikoto Tarao (2007) [122 ] J K73.9 (chronic hepatitis) RCT 156 No No 2 K K shosaikoto, juzentaihoto Okuma (1993) [123 ] J L70.0 (cne vulgaris) RCT 268 R No 5 K S, K jumihaidokuto, orengedokuto Nishizawa et al. (2004) [124 ] J M35.0 (sicca syndrome) RCT 847 R No 2 K S bakumondoto Nishizawa et al. (2003) [125 ] J M35.0 (Sicca syndrome) RCT 756 R No 2 K S bakumondoto Nishizawa et al. (2002) [126 ] J M35.0 (Sicca syndrome) RCT 105 C No 2 K S bakumondoto Hayashi et al. (1994) [127 ] J M48.0 (spinal stenosis) Quasi-RCT 27 R No 2 K S hachimijiogan Maejima and Katayama (2004) [128 ] J M48.02 (chronic lumbar pain) RCT 89 R No 3 K S, K goshajinkigan, shuchibushimatsu Nishizawa et al. (2007) [129 ] J N32.8 (overactive bladder) RCT 704 No No 2 K S goshajinkigan Iwabuchi (2000) [130 ] J N93.9 (dysfunctional uterine bleeding) Case Control 183 No No 2 K S kyukikyogaito Takamatsu (2006) [131 ] J N95.1 (menopausal syndrome) Quasi-RCT 170 No No 2 K S tokishakuyakusan, kamishoyosan keishibukuryogan
Ushiroyama et al. (2005) [132 ] E N95.8 (menopausal syndrome) RCT 131 R No 2 K S keishibukuryogan Matsuo et al. (2005) [133 ] J N95.8 (menopausal syndrome) RCT-cross over 24 R No 2 SK S tokishakuyakusan Ota et al. (2001) [134 ] J N95.8 (menopausal syndrome) RCT 96 R No 2 K S keishibukuryogan, kamishoyosan,goshajinkigan, tokishakuyakusan, tokakujokito, kihito, nyoshinsan Ushiroyama et al. (2006) [135 ] J O03.9 (uterine hemorrhage) RCT 72 R No 2 K S kyukikyugaito Wada et al. (2003) [136 ] J O90.9 (postpartum condition) RCT 60 R No 2 K S kyukichoketsuin Sakuma et al. (2002) [137 ] J O90.9 (postpartum psycho-physical condition) RCT 171 R No 2 K S kyukichoketsuin Takushima and Inoguchi (2001) [138 ] J O90.9 (puerperium) Case Control 47 No No 2 K S kyukichoketsuin Nishizawa et al. (2003) [139 ] J R05 (cough) RCT 2069 R No 2 K S bakumondoto Motoo et al. (2005) [140 ] E T37.5 (ribavirin-induced anemia) RCT 23 R No 2 K S ninjinyoeito Hushiki et al. (2003) [141 ] J T45.4 (gastritis due to oral iron) RCT 120 R No 2 SK S rikkunshito Imazato et al. (1998) [142 ] J Z01.8 (pretreatment of barium enema) RCT 60 R No 2 SK S shakuyakukanzoto Yokota et al. (1990) [143 ] J Z01.8 (pretreatment of barium enema) RCT 60 R No 2 K S daiokanzoto Saida et al. (2003) [144 ] J Z01.8 (pretreatment for bowel endscopy) RCT 70 E No 2 SK S shakuyakukanzoto Ohnishi et al. (1999) [145 ] E Z01.9 (pharmacokinetics with carbamazepine) RCT-cross over 4 R No 2 SK S shoseiryuto Saida et al. (2005) [146 ] E Z03.1 (pretreatment of colonoscopy) RCT 285 E No 2 SK S daikenchuto
Sugihara (1999) [147 ] J Z03.1 (gastric endoscopy) Case Control 58 No No 2 SK S shakuyakukanzoto Mizukami et al. (2007) [148 ] J Z03.8 (pretreatment of colonoscopy) Quasi-RCT 42 No No 2 SK S shakuyakukanzoto Ai et al. (2006) [149 ] E Z03.8 (pretreatment of colonoscopy) RCT 110 R No 2 K S shakuyakukanzoto
