Evidence-Based Complementary and Alternative Medicine / 2011 / Article / Tab 1

Research Article

Evaluation of Traditional Indian Antidiabetic Medicinal Plants for Human Pancreatic Amylase Inhibitory Effect In Vitro

Table 1

Plant sources and their traditional uses.

Plants name V. no FamilyParts usedHypoglycemic and medicinal propertiesRef.

Azadirachta indica A. Juss. (Neem)GMAI3MeliaceaeLeavesAntihyperglycemic activity, increase in glucose uptake and glycogen deposition, inhibits activity of epinephrine on glucose metabolism resulting in utilization of peripheral glucose. Does not alter cortisol concentration.[17, 18]
Bixa orellana L. (Sindhuri)BOSP1BixaceaeLeavesHypoglycemic activity by lowering blood glucose by stimulating peripheral utilization of glucose.[19]
Bougainvillea spectabilis Willd. (Bougainvilla)MARCKBS2NyctaginaceaeLeavesHypoglycemic effect is by D-pinitol which exerts insulin-like effect and inhibits α-glucosidase.[20]
Cinnamomum verum J.S.Presl (Cinnamon)CIZYS1LauraceaeLeavesHypoglycemic activity is by enhancing insulin activity, increasing lipid metabolism and antioxidant status, capillary function.[21]
Curcuma longa L. (Turmeric)SUCL1ZingiberaceaeRhizomeHypoglycemic, hypolipidemic, and antioxidant property. Decreased influx of glucose in polyol pathway, increasing NADPH/NADP ratio and increased activity of glucose peroxidase.[22]
Ficus bengalensis L. (Banyan)GMFB1MoraceaeLeaves, BarkStimulates insulin secretion from beta cells inhibits insulin degradative process. [23]
Ficus recemosa L. (Umbar)GMFR2MoraceaeFruit pulpHypoglycemic activity by β-sitosterol isolated was found to lower the blood glucose level.[24]
Momordica charantia L. (Karela,)
(Bitter gourd)
MARCK1CucurbitaceaeLeaves, fruit, seedsHypoglycemic effect by inhibition of glucose-6-phosphatase and fructose-1-6-biphosphatase in liver and stimulation of hepatic glucose-6-phosphate dehydrogenase.[25]
Murraya koenigii L. Spreng
(Curry Leaves)
SP-2RutaceaeLeavesIncreases glucogenesis and decreases glycogenolysis and gluconeogenesis. [26]
Syzygium cumini L. Skeels (Jamun)SPSC2MyrtaceaeSeedsReduces blood glucose level, increase in serum insulin level, exhibits insulinase activity. Hypoglycemic activity mediated through insulin release mechanism, glycogen content and hepatic glucokinase, hexokinase, glucose-6-phosphate, and phosphofructokinase levels in diabetic mice.[4, 17]
Tribulus terrestris L. (Gokshura) SUTT1 ZygophyllaceaeSeeds Hypoglycemic activity by inhibiting oxidative stress.[16]

The common Indian name for the plant is given in brackets.
Voucher numbers as given by Botanical Survey of India, Pune.

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