Research Article

Anticancer Potentials of Root Extract of Polygala senega and Its PLGA Nanoparticles-Encapsulated Form

Figure 6

(a) EEPS and NEEPS induced apoptosis in A549 cells. Cells were harvested and stained with Annexin V-FITC and propidium iodide (PI). Ten thousand events were collected and analysed for each sample. (i) Control, (ii)-(iii) Cells treated with two doses of EEPS (100 and 200  g), and (iv)-(v) Cells treated with two doses of NEEPS (100 and 200  g). (b) Histogram represents percentages of cell population (viable, early apoptotic, late apoptotic, and necrotic cells) in different series by Annexin V-FITC assay. Values represent mean ± SE ( ). Significant differences between EEPS and NEEPS are indicated by *( ) and **( ).
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