Research Article

The In Vivo Antidiabetic Activity of Nigella sativa Is Mediated through Activation of the AMPK Pathway and Increased Muscle Glut4 Content

Figure 3

Effect of NSE on plasma insulin levels in Meriones shawi. The plasma insulin was measured after 4 weeks of treatment in diabetic control group (DC), normal control group (NC), and animals receiving 48 mg/kg/day N. sativa ethanolic extract (NSE) or 300 mg/kg/day of the reference oral antidiabetic drug metformin. Results are expressed as mean ± SEM ( ). Significantly different from diabetic control animals (DC) * . Significantly different from normal (non-diabetic) control animals (NC) $ .
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