Research Article

The In Vivo Antidiabetic Activity of Nigella sativa Is Mediated through Activation of the AMPK Pathway and Increased Muscle Glut4 Content

Table 1

Evolution of body weight over the course of the 4-week treatment.

Time (week)N. sativa (g ± SEM)Metformin (g ± SEM)Diabetic control (g ± SEM)Normal control (g ± SEM)

0178 ± 17177 ± 11187 ± 15158 ± 14
1172 ± 16166 ± 11178 ± 15153 ± 12
2183 ± 19180 ± 10186 ± 15161 ± 13
3185 ± 18 183 ± 9192 ± 16166 ± 13
4184 ± 16 184 ± 9197 ± 15170 ± 12

No statistically significant differences were observed between experimental groups at any of the time points ( per group, N.S.).