Review Article
Herbal Medicine and Hepatocellular Carcinoma: Applications and Challenges
Table 2
Summary of anti-HCC herbal composite formula.
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Herbal composite formula
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Possible mechanisms of anti-HCC
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References
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| Shi-Quan-Da-Bu-Tang (TJ-48) | Inhibits tumors growth, reduces oxidative DNA damage, inflammatory cell infiltration and cytokine expression | [76] | Sho-saiko-to (TJ-9) | Increases TNF- and G-CSF; inhibits 8-OHdG formation; reduces the number of pre-neoplastic cells; cell-killing effect | [77ā80] | Bu-Zhong-Yi-Qi-Tang | Stimulates productions of G-CSF and TNF- | [81] | Shenqi mixture (SQM) | Increases CD3+, CD4+, CD4+/CD8+, NK activity | [82] | Xiaoliu Pingyi Mixture (XLPY) | Inhibits growth; induces apoptosis; inhibits Bcl-2 gene | [83] | Sihoga-Yonggol-Moryo-Tang (SGYMT) | Inhibits MMP-2 and MMP-9; inhibits tumor invasion | [79] | QHF | Inhibits the growth of HCC | [84] | Fuzheng Jiedu Decoction (FJD) | Enhances PTEN; inhibits tumor invasion | [85] | Star-99 | Inhibits the growth of HCC; induces apoptosis | [86] |
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