Modulation of Hypoxia-Induced Pulmonary Vascular Leakage in Rats by Seabuckthorn (Hippophae rhamnoides L.)

Table 2

Circulating levels of epinephrine, norepinephrine and dopamine in animals pretreated with DEXA, SBT LE (100 mg/kg bw) following exposure to hypoxia of 9144 m for 5 h.

	Control	Hypoxia	DEXA 5 mg/kg bw	SBT SL 100 mg/kg bw
Epinephrine (pg/mL)	122.07±90.31	956.92±884.12^∗∗	406.96±361.17^∗#	739.46±490.22^∗∗
Norepinephrine (pg/mL)	103.23±67.74	1201±880.14^∗∗	296.30±168.71^∗∗##	781.85±528.38^∗∗#
Dopamine (pg/mL)	34.46±28.45	1508.44±716.25^∗	138.84±406.46^##	460.15±348.58^∗#

Values are expressed as mean ± SD (𝑛=16 per group). Significant test between groups were determined by using one-way ANOVA followed by Tukey test.
* 𝑃<.05 versus Control; **𝑃<.01 versus Control; ^#𝑃<.05 versus hypoxia; ^##𝑃<.01 versus hypoxia.