Cytotoxic Effects of Bangladeshi Medicinal Plant Extracts
Table 2
Cytotoxic activity (IC50) of Bangladeshi plant extracts.
Species name
Part used
Extract
Yields (%)
Cytotoxic activity (IC50) mg mL−1)
NIH/3T3
AGS
HT29
MDA-MB-435S
Acrostichum aureum
L
M
0.64
>2.50
1.02
>2.50
>2.50
W
2.94
>2.50
>2.50
>2.50
>2.50
Adiantum caudatum
L
M
11.14
1.88
1.75
1.48
1.23
W
8.04
>2.50
>2.50
>2.50
>2.50
Aegiceras corniculatum
B
M
6.39
0.02
>2.50
0.33
0.66
W
1.40
>2.50
1.68
NC
1.91
Argemone mexicana
L
M
5.28
>2.50
>2.50
>2.50
1.82
W
10.90
>2.50
>2.50
>2.50
>2.50
Ammannia baccifera
L
M
20.16
>2.50
0.55
0.59
0.91
W
4.25
>2.50
>2.50
>2.50
>2.50
Blumea lacera
L
M
15.41
0.01
0.03
0.07
0.08
W
16.15
0.67
0.99
0.48
0.39
Bruguiera gymnorrhiza
L
M
4.42
NC
>2.50
>2.50
>2.50
W
2.15
>2.50
>2.50
>2.50
1.38
Clerodendron inerme
L
M
1.43
>2.50
2.38
>2.50
>2.50
W
3.24
>2.50
>2.50
>2.50
>2.50
Cynometra ramiflora
B
M
6.16
>2.50
>2.50
1.79
2.35
W
2.91
>2.50
>2.50
>2.50
>2.50
Ficus religiosa
L
M
1.14
1.01
2.16
>2.50
>2.50
W
1.33
>2.50
NC
>2.50
>2.50
Hibiscus tiliaceous
L
M
4.84
NC
2.50
>2.50
1.14
W
5.94
1.11
0.25
0.80
1.09
Hygrophila auriculata
S
M
0.51
NC
>2.50
>2.50
1.58
W
4.36
>2.50
>2.50
0.22
1.40
Limnophila indica
L
M
11.14
>2.50
>2.50
2.19
1.24
W
5.04
NC
2.24
NC
1.25
Mollugo pentaphylla
WP
M
6.22
>2.50
>2.50
>2.50
>2.50
W
3.97
>2.50
>2.50
NC
>2.50
Pandanus foetidus
L
M
5.70
>2.50
NC
>2.50
>2.50
W
4.45
NC
>2.50
>2.50
>2.50
Xylocarpus moluccensis
P
M
20.07
>2.50
0.62
>2.50
1.08
W
5.42
>2.50
>2.50
>2.50
1.78
B: bark; L: leaves; S: seeds; WP: whole plant; P: pneumatophore; M: methanolic extract; W: aqueous extract; : no cytotoxicity at a concentration up to 2.5 mg mL−1; IC50 (50% inhibition of cell growth) calculated by probit analysis software, data was generated from two independent experiments, each experiment performed in triplicates.
