Proteomic Analysis of Anti-inflammatory Effects of a Kampo (Japanese Herbal) Medicine “Shoseiryuto (Xiao-Qing-Long-Tang)” on Airway Inflammation in a Mouse Model
Figure 2
Effects of SST and prednisolone on lung tissue eosinophilia, hypertrophied smooth muscle and mucus secretion in OVA-sensitized mice were measured. Non-sensitized BALB/c mice were treated p.o. with water (a and e), and OVA-sensitized mice were treated p.o. with water (b and f), SST (0.5 g kg−1) (c and g) or prednisolone (3 mg kg−1) (d and h) five times from day 1 to 6 after OVA exposure. Lung tissues were removed at 7 days after OVA exposure and stained with hematoxylin and eosin (a–d) or periodic acid-Schiff (e–h) as described in “Methods” section. Magnification ×100.