Figure 1: Effect of a unilateral intra-articular injection of monosodium iodoacetate (3 mg/50 μL/rat) on the weight-bearing ability of hind legs (n = 8). Note that iodoacetate-injected rats bore significantly less weight on the ipsilateral hind limb than did saline-injected rats. Abscissas: the time points from the 1st to the 7th day after iodoacetate; ordinate: body weight difference. *** versus saline.