3,4-Di-O-Caffeoylquinic Acid Inhibits Angiotensin-II-Induced Vascular Smooth Muscle Cell Proliferation and Migration by Downregulating the JNK and PI3K/Akt Signaling Pathways

Figure 1

Various anti-oxidative properties by CQC. In cell free system, CQC displayed potent antioxidant activity to inhibit Cu²⁺-induced oxidation of human LDL (a) and scavenge DPPH free radical (b). In cultured HUVECs, CQC minimized not only the loss of cell viability induced by oxidative stress but also the ROS-induced impairment of endothelium-dependent relaxation to acetylcholine in rat aorta (c).

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(b)

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