3,4-Di-O-Caffeoylquinic Acid Inhibits Angiotensin-II-Induced Vascular Smooth Muscle Cell Proliferation and Migration by Downregulating the JNK and PI3K/Akt Signaling Pathways
Figure 3
rVSMC migration. (a)
Concentration-dependent response of Ang-II-induced rVSMC migration.
(b) 3,4-di-O-caffeoylquinic acid dose-dependently
inhibited 100 nM Ang-II-induced migration.
and , significant difference versus samples
treated with Ang II alone. Each histogram represents the mean ± SE of three
separate experiments run in triplicate on four separate cultures.