Original Article

3,4-Di-O-Caffeoylquinic Acid Inhibits Angiotensin-II-Induced Vascular Smooth Muscle Cell Proliferation and Migration by Downregulating the JNK and PI3K/Akt Signaling Pathways

Figure 3

rVSMC migration. (a) Concentration-dependent response of Ang-II-induced rVSMC migration. (b) 3,4-di-O-caffeoylquinic acid dose-dependently inhibited 100 nM Ang-II-induced migration. and , significant difference versus samples treated with Ang II alone. Each histogram represents the mean ± SE of three separate experiments run in triplicate on four separate cultures.
634502.fig.003a
(a)
634502.fig.003b
(b)