Systematic Review of Integrative Health Care Research: Randomized Control Trials, Clinical Controlled Trials, and Meta-Analysis

Table 2

SAS-CT Adverse Events Scoring.

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The safety assessment score for controlled clinical trials (SAS-CT) consists of six major domains. Each domain and subgroup has different weightings according to its degree of important and rate of occurrence.

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The maximum subscores of:

(i) adverse events definitely not related to the intervention (AEs-NR) and adverse drug reactions (ADRs) are 27 points,

(ii) serious adverse events definitely not related to the intervention (SAEs-NR) and serious adverse drug reactions (SADRs) are 13.5     points,

(iii) drop-outs due to AE/SAEs-NR and ADRs/ SADRs have a maximum subscore of 9.5 points each.

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Total SAS-CT score per control clinical trial equals 100 points.

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Quality is based on the degree of the importance of the subdomains.

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The SAS-CT is separated into three quality levels:

(i) poor (0 < SAS-CT < 28)

(ii) medium (28 < SAS-CT < 68)

(iii) high quality safety reporting (68 < SAS-CT < 100)

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