Selective Th2 Upregulation by Crocus sativus: A Neutraceutical Spice

Table 1

Immunomodulatory activity of ACS on Humoral (Antibody titre) and cell-mediated immune response (CMI) in normal Balb/c mice.

Test material	Dose; mg/kg; p.o.	Humoral response; antibody titre	CMI response; foot thickness; (mm) 24 h
Control	—
ACS	1.56	(13.91↑)	(8.82↑)
ACS	3.12	(14.88↑)	(10.29↑)
ACS	6.25	(29.93↑)	(14.70↑)
ACS	12.50	(29.61↑)	(13.23↑)
ACS	25.00	(23.46↑)	(11.76↑)
ACS	50.00	(19.74↑)	(7.35↑)
Levamisole	2.5	(35.76↑)	(29.14↑)
Cyclosporine	5.00	(36.56↓)	(38.23↓)

Value in parentheses signify percentage activity in agglutinating antibody titre and CMI Response
↓ : Percent Decrease, ↑ : Percent Increase
,
All values are shown as .
P-value:;,
P-values were calculated by Student’s .