Case Report

Herbal Medicine Containing Licorice May Be Contraindicated for a Patient with an HSD11B2 Mutation

Figure 3

Schematic drawing of the pathogenesis of the patient. The patient was heterozygous for a mutation in HSD11B2 (“normal/mutant" alleles in the figure), suggesting that her 11βHSD2 enzyme activity in the kidney was reduced. Without licorice loading, she was able to keep her healthy condition. However, with licorice loading, she showed serious hypertension.
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