The Ethanol Extract of Fructus trichosanthis Promotes Fetal Hemoglobin Production via p38 MAPK Activation and ERK Inactivation in K562 Cells
The effect of FT-EtOH extract on the cell viability and THb induction in K562 cells. (i) K562 cells were treated with indicated concentrations of FT-EtOH extract for 2 days. The cell viability (filled square) was then estimated by MTT assay. (ii) K562 cells were treated with indicated concentrations of FT extract for 6 days. The Hb-positive cells were stained by TMB assay and the percentage of stained cells (filled triangle) was calculated. The results are expressed as mean SD of three cultures. The data are representative of three separate experiments. #, significant difference in cell viability when compared with non-treated group. *, significant difference in the number of TMB-stained cells when compared with non-treated group.
Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.