In Vitro and In Vivo Activities of Essential Oil from the Seed of Anethum graveolens L. against Candida spp.

Figure 4

Microscopic observation of therapeutic efficacy of essential oil versus FCZ against vaginal candidiasis in BALB/c mice on Post-infection day 4, day 8, day 15 (periodic acid-Schiff staining, 400x). CK: neither infected nor treated animals. Group 1: infected, untreated but not immunosuppressed animals. Group 2: immunosuppressed, inoculated intravaginally with C. albicans 09-1555, received excipient. Group T1: treated groups:immunosuppressed, infected animals received FCZ (20 μL at 100 μg/mL). Groups T2, T3, T4 treated groups: immunosuppressed, infected animals received essential oils (20 μL at 2% v/v, 1% v/v, 0.0625% v/v). The bar is 10 μm.