Scorpion in Combination with Gypsum: Novel Antidiabetic Activities in Streptozotocin-Induced Diabetic Mice by Up-Regulating Pancreatic PPARγ and PDX-1 Expressions

Table 2

Changes in body weights, water and dietary intake in mice after 5 weeks of treatment.

	Body weight (g)		Water intake (ml g^−1 body weight)	Diet intake (g g^−1 body weight)
	Before treatment	After treatment
N	32.1 ± 1.3	40.7 ± 2.4	0.24 ± 0.07	0.178 ± 0.048
D	27.4 ± 4.6*	29.2 ± 3.9**	0.72 ± 0.12**	0.365 ± 0.015**
D + SG	26.9 ± 5.6	34.4 ± 2.3*	0.35 ± 0.09**	0.305 ± 0.016**
D + G	26.3 ± 2.2	30.8 ± 6.5	0.45 ± 0.08*	0.359 ± 0.020
D + S	27.1 ± 4.1	34.7 ± 3.4*	0.66 ± 0.10	0.342 ± 0.053
D + M	26.7 ± 3.3	34.9 ± 4.2*	0.40 ± 0.07**	0.345 ± 0.022

N: Normal control mice; D: diabetic control mice; D + SG: diabetic mice treated with scorpion (350 mg kg⁻¹ per day) combined with gypsum (350 mg kg⁻¹ per day); D + G: diabetic mice treated with gypsum (350 mg kg⁻¹ per day); D + S: diabetic mice treated with scorpion (350 mg kg⁻¹ per day); D + M: diabetic mice treated with metformin (250 mg kg⁻¹ per day). Data were expressed as mean ± SD (n = 10). *𝑃<.05, **𝑃<.01 “D” versus “N”; *𝑃<.05, **𝑃<.01 “D + SG” versus “D”; *𝑃<.05 “D + G” versus “D”; *𝑃<.05 “D + S” versus “D”; *𝑃<.05, **𝑃<.01 “D + M” versus “D”.