Antiosteoporotic Activity of Dioscorea alata L. cv. Phyto through Driving Mesenchymal Stem Cells Differentiation for Bone Formation
Figure 6
Effect of Dispo85E on trabecular bone volume in OVX mouse model. C57BL/6 mice were sham operated (a) or OVX. The OVX mice were fed 0 mg/kg/day (vehicle control) (b), 40 mg/kg/day (c), 200 mg/kg/day (d), or 1000 mg/kg/day (e) Dispo85E for 42 days. The femora were collected 42 days after the operation, and the sections of distal femoral metaphysis were stained with Hematoxylin-eosin. Arrow indicates the trabecular bone. (f) Histomorphometric measurements of bone volume/total bone volume percentage (BV/TV, %) were performed. Measurement was performed at a magnification of 40-fold. **Indicates significant difference from OVX mice at . for each group.
