Metabolism and Pharmacokinetics of San-Huang-Xie-Xin-Tang, a Polyphenol-Rich Chinese Medicine Formula, in Rats and <i>Ex-Vivo</i> Antioxidant Activity

<table class="table-group" id="tab3"><tr><td><table class="table"><tr><td class="thead-hr" colspan="6"><hr/></td></tr><tr class="thead"><td align="left"></td><td align="left">Baicalein</td><td align="left">Aloe- emodin</td><td align="left">Rhein</td><td align="left">Emodin</td><td align="left">Chrysophanol</td></tr><tr><td class="thead-hr" colspan="6"><hr/></td></tr><tr><td align="left">Free form</td><td align="left">ND</td><td align="left">ND</td><td align="left">2.1</td><td align="left">ND</td><td align="left">ND</td></tr><tr><td align="left">Sulfates/ glucuronides</td><td align="left">1.8</td><td align="left">1.3</td><td align="left">7.9</td><td align="left">0.7</td><td align="left">3.9</td></tr><tr><td align="left">Glucuronides</td><td align="left">1.1</td><td align="left">0.2</td><td align="left">1.5</td><td align="left">0.5</td><td align="left">1.3</td></tr><tr class="table-tr"><td colspan="6"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-fn"><td>ND: not detected.<br/></td></tr></table>

Contents (<i>μ</i>mol ml<sup>−1</sup>) of various constituents in 1-fold serum level of SHXXT metabolite used for anti-hemolysis test.

Evidence-Based Complementary and Alternative Medicine

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Table 3

Table 3: Metabolism and Pharmacokinetics of San-Huang-Xie-Xin-Tang, a Polyphenol-Rich Chinese Medicine Formula, in Rats and <i>Ex-Vivo</i> Antioxidant Activity 

Table 3 | Metabolism and Pharmacokinetics of San-Huang-Xie-Xin-Tang, a Polyphenol-Rich Chinese Medicine Formula, in Rats and Ex-Vivo Antioxidant Activity 