Anti-Inflammatory, Immunomodulatory, and Heme Oxygenase-1 Inhibitory Activities of Ravan Napas, a Formulation of Uighur Traditional Medicine, in a Rat Model of Allergic Asthma
Figure 4
Effect of Ravan Napas (RN) on sICAM-1 and total IgE concentration in serum of OVA-induced rat model of asthma. Blood was sampled and serum obtained 24 h after last OVA challenge. sICAM-1 and total IgE were measured by ELISA as described in the materials and methods section. (a): sICAM-1 concentrations; (b): IgE concentrations; Normal: rats sensitized with OVA and challenged with saline. Control: rats sensitized and challenged with OVA. DXM: OVA-sensitized and challenged rats treated with Dexamethasone (10 mg/kg). RN-1: OVA-sensitized and challenged rats treated with RN (0.25 g/kg/day). RN-2: OVA-sensitized and challenged rats treated with RN (0.5 g/kg/day). Data are expressed as , rats per group. versus Normal; versus Control.
