Nordihydroguaiaretic Acid from Creosote Bush (Larrea tridentata) Mitigates 12-O-Tetradecanoylphorbol-13-Acetate-Induced Inflammatory and Oxidative Stress Responses of Tumor Promotion Cascade in Mouse Skin
Figure 3
Effect of NDGA on TPA-induced (a) lipid peroxidation, (b) H2O2 production and (c) xanthine oxidase activity in skin of mice from different treatment groups. Values are expressed as means ± SE (n = 6) of nmol TBARS formed/h/g tissue, nmol H2O2/h/g tissue and μg uric acid/mg protein, respectively. Significant differences are indicated by ***P .001 when compared with control animals (Group I) and #P .05 and ###P .001 and when compared with TPA-treated animals (Group II).
