Nordihydroguaiaretic Acid from Creosote Bush (Larrea tridentata) Mitigates 12-O-Tetradecanoylphorbol-13-Acetate-Induced Inflammatory and Oxidative Stress Responses of Tumor Promotion Cascade in Mouse Skin
Figure 4
Effect of NDGA on TPA induced (a) GSH level, (b) GPx, (c) GR and (d) GST activity in mouse skin from different treatment groups. Values are expressed as means ± SE (n = 6) of GSH/g tissue, GPx and GR activities as nmol NADPH oxidized/min/mg protein, GST activity as nmol CDNB conjugates formed/min/mg protein. Significant differences are indicated by ***P .001 when compared with control animals (Group I) and #P .05, ##P .01 and ###P .001 and when compared with TPA-treated animals (Group II).
