Aqueous Extract of Brazilian Green Propolis: Primary Components, Evaluation of Inflammation and Wound Healing by Using Subcutaneous Implanted Sponges
Figure 3
Representative histological sections of sponge implants (5 μm stained with Picrossirius-red) for collagen assessment from control (a, c, and e) and propolis-treated (b, d, and f). The implant was progressively infiltrated by thin collagen (green area) up to 7 days in both groups. After 14 days post implantation, the sponge matrix was predominantly occupied by dense collagen (red and yellow areas) in the propolis-treated and control groups. The collagen area in the propolis-treated group was significantly reduced compared with the control group at days 4, 7 and 14 (arrow heads indicate the most important areas). Bar: 16 μm.
