Ethanol Extract of Chinese Propolis Facilitates Functional Recovery of Locomotor Activity after Spinal Cord Injury

Figure 4

Hypothetical diagram showing mechanism of the effect of EECP on spinal cord neurotrauma. EECP attenuates the expression iNOS mRNA, probably derived from macrophages that have infiltrated into the lesioned area. Furthermore, EECP increases BDNF and NT-3 gene expression in the injured spinal cord, which may protect neurons and myelin (elaborated by oligodendrocytes) and/or cause regeneration of the transected axons. These effects of EECP may partially contribute to the decreased lesion area and improved locomotor function after SCI.