Different Influences on Tacrolimus Pharmacokinetics by Coadministrations of Zhi Ke and Zhi Shi in Rats

<table>Mean (±S.D.) blood concentration-time profiles of tacrolimus after oral administration of tacrolimus alone (1.5 mg/kg) (°) and coadministrations with 2 g/kg of Zhi Ke (●) and Zhi Shi (<i>▾</i>) decoctions.</table>

Evidence-Based Complementary and Alternative Medicine

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Figure 2

Figure 2: Different Influences on Tacrolimus Pharmacokinetics by Coadministrations of Zhi Ke and Zhi Shi in Rats 