Original Article

Neuroprotection Offered by Majun Khadar, a Traditional Unani Medicine, during Cerebral Ischemic Damage in Rats

Table 2

Effect of cerebral ischemia on the activity of various enzymes in the hippocampus.

EnzymesSHAMMCAOMCAO + MKMK ONLY

GP×16.30 ± 0.937.59 ± 0.52 12.86 ± 1.22 16.00 ± 1.02
(53.43%)(69.43%)(−1.84%)
GR34.54 ± 1.5021.65 ± 1.04 27.81 ± 1.06 33.70 ± 1.41
(37.31%)(28.45%)(−2.43%)
GST16.29 ± 0.729.37 ± 0.63 12.58 ± 0.98 16.92 ± 0.8l
(42.48%)(34.25%)(15.83%)
CAT6.38 ± 0.333.23 ± 0.21 4.86 ± 0.38 5.37 ± 0.41
(49.37%)(50.46%)(−15.83%)
Na+K+4.52 ± 0.252.21 ± 0.13 3.46 ± 0.26 4.21 ± 0.24
ATPase(51.10%)(56.56%)(−6.8%)

Values are expressed as mean ± S.E (n = 6) in nmoles/minutes/mg protein. Values in parentheses show the percentage increase or decrease with respect to their control. Significance was determined as P < .001 sham versus MCAO. P < .01; P < .05 MCAO versus MCAO + MK.