Role of Apoptotic Proteins in REC-2006 Mediated Radiation Protection in Hepatoma Cell Lines
Figure 4
Effect of optimal concentration of drug (REC-2006), that is, 10−5μg mL−1 given 2 h prior to irradiation (LD80 of respective cell lines) on expression of (a) cytochrome c; (b) Apaf-1; (c) caspase-9; (d) caspase-3 in HepG2 and Hep3B cell lines. Single asterisk indicates significant radiomodulatory activity (increase/decrease in expression) in HepG2 cell lines, whereas double asterisks indicate the corresponding effect in Hep3B cell lines with respect to radiation (LD80) controls.
