Research Article

Anti-Arthritic Activity of Bartogenic Acid Isolated from Fruits of Barringtonia racemosa Roxb. (Lecythidaceae)

Table 2

Primary and secondary arthritic lesions at 21st day in CFA-induced arthritis in rats.

TreatmentPrimary lesions (% rise in injected paw volume)Secondary lesions (% rise in non-injected paw volume)

CFA control146 ± 4.419 ± 0.67
Diclofenac (5 mg kg−1  day−1, p.o.)83 ± 4.4**13 ± 0.63**
BA (2 mg kg−1 day−1, p.o.)113 ± 7.6**15 ± 0.65**
BA (5 mg kg−1 day−1, p.o.)109 ± 3.3**12 ± 0.53**
BA (10 mg kg−1 day−1, p.o.)91 ± 2.7**11 ± 0.57**

Data represented in mean ± SEM (n = 6).
** P < .01, compared with control group.