Anti-Arthritic Activity of Bartogenic Acid Isolated from Fruits of Barringtonia racemosa Roxb. (Lecythidaceae)

Table 4

Alterations in hematological parameters, CRP and RF in CFA-induced arthritis in rats.

Group	RBC (×10^6/mm^3)	WBC (×10^3/mm^3)	ESR (mm/h)	Hb (mg%)	CRP (mg/dL)	RF (IU/mL)
CFA control	7.3 ± 0.2	13 ± 0.4	14 ± 0.3	12 ± 0.4	8.8 ± 0.8	73 ± 6.7
Diclofenac (5 mg kg^−1 day^−1, p.o.)	9.2 ± 0.2**	5.5 ± 0.2**	10 ± 0.2**	15 ± 0.3**	1.8 ± 0.3**	23 ± 3.3**
BA (2 mg kg^−1 day^−1, p.o.)	8 ± 0.3	7.5 ± 0.3**	12 ± 0.2**	13 ± 0.5	4.4 ± 0.4**	37 ± 3.3**
BA (5 mg kg^−1 day^−1, p.o.)	9 ± 0.2**	7.2 ± 0.3**	13 ± 0.3	15 ± 0.4**	2.2 ± 0.2**	33 ± 4.2**
BA (10 mg kg^−1 day^−1, p.o.)	9.8 ± 0.2**	5.6 ± 0.2**	11 ± 0.3**	16 ± 0.3**	1.4 ± 0.2**	23 ± 3.3**

Data represented in mean ± SEM (n = 6).
** P < .01, compared with control group.