Role of Bone Morphogenetic Proteins-7 (BMP-7) in the Renal Improvement Effect of DangGui (Angelica sinensis) in Type-1 Diabetic Rats
Figure 3
Change of the BMP-7 level in the kidney of STZ-diabetic rat after 1-week (a) or 4-week (b) treatment of DangGui (5 mg/kg) or ramipril (1 mg/kg). Western blotting analysis of BMP-7 expression was carried out in the kidney of 9-week STZ-diabetic rat. Upper picture shows the protein level of BMP-7 or β-actin in kidney isolated from STZ-diabetic rat. The different treatments on rats are described in the Materials section. Quantification of protein level using BMP-7/β-actin expressed as mean ± SE (n = 4 per group) in each column is indicated in the lower panel. *P < 0.05 compared to the value of vehicle-treated normal rats.
