Triterpenic Acids Present in Hawthorn Lower Plasma Cholesterol by Inhibiting Intestinal ACAT Activity in Hamsters

Table 5

Fecal output and fecal excretion of plant sterols, neutral sterols and bile acids in hamsters fed the control and treatment diets.

Fecal	Diets
	Control	Hawthorn	PSE	Hawthorn + PSE	OA + UA
Fecal output (g/day)
Dry weight	0.63 ± 0.03	0.62 ± 0.03	0.57 ± 0.03	0.61 ± 0.03	0.63 ± 0.02
Fecal excretion of sterols and bile acids (𝜇mol/day)
Plant sterols	2.19 ± 0.07	2.63 ± 0.17 (+20%)	16.35 ± 1.13 (+647%)**	17.86 ± 1.09 (+716%)**	2.40 ± 0.10 (+9%)
Neutral sterols	9.90 ± 0.43	11.54 ± 0.54 (+17%)*	10.24 ± 0.57 (+3%)	11.58 ± 0.78 (+17%)*	12.14 ± 0.46 (+23%)*
Bile acids	1.68 ± 0.13	1.42 ± 0.14 (−15%)*	1.64 ± 0.16 (−2%)	1.31 ± 0.10 (−22%)*	1.30 ± 0.11 (−23%)*
Neutral sterols +   Bile acids	11.71 ± 0.47	13.04 ± 0.61 (+11%)	11.97 ± 0.66 (+2%)	12.85 ± 0.76 (+10%)	13.47 ± 0.49 (+15%)

PSE: plant sterol esters. Forty-eight hours fecal samples were collected in Week 3. Plant sterols include campesterol, campestanol, stigmasterol, stigmastanol, beta-sitosterol, sitostanol and brassicasterol. Neutral sterols include cholesterol, cholestanol and coprostanone. Values are means ± SEM (n = 20 animals per group). Data in parenthesis represent percentage difference compared to control group.
* P < .05; **P < .01.