Hemidesmus indicus and Hibiscus rosa-sinensis Affect Ischemia Reperfusion Injury in Isolated Rat Hearts

Table 1

Effect of 15-min perfusion with HI and HRS on hemodynamic parameters of the isolated rat heart. LVDP: left ventricular developed pressure (LV systolic minus diastolic pressure); HR: heart rate; CF: coronary flow; BD: Before Drug (pre-drug values). ^∗𝑃<.05, ^∗∗𝑃<.01 versus BD (baseline).

	BD	HI			BD	HRS
		pre-ischemia				pre-ischemia
		HI 90	HI 180	HI 360		HRS 90	HRS 180	HRS 360
LVDP (mmHg)	89.5 ± 9.1	83.9 ± 2.2	84.8 ± 1.9	82.2 ± 7.5	83.9 ± 4.0	77.6 ± 3.5	82.6 ± 3.2	80.7 ± 2.8
HR (BPM)	302.6 ± 22.6	290.1 ± 31.5	286.6 ± 9.7	299.4 ± 33.1	305.8 ± 11.4	284.1 ± 9.3	290.0 ± 23.8	292.1 ± 13.8
CF (mL/min)	8.8 ± 0.3	14.1 ± 2.8	17.7 ± 2.5∗	20.6 ± 2.7∗∗	8.8 ± 0.4	10.5 ± 0.9	11.0 ± 2.2	12.4 ± 1.6