Original Article
Black Cohosh Hepatic Safety: Follow-Up of 107 Patients Consuming a Special Cimicifuga racemosa rhizome Herbal Extract and Review of Literature
Table 2
Follow up of patients assuming Cimicifuga.
| Parameter | Values |
| Physical examination | | BMI | 28.5 (SD 0.71) | Blood pressure | | systolic | 125 (SD 7.07) | diastolic | 75 (SD 21.21) | Heart rate | 76.5 (SD 0.71) |
Few patients (9/107) were suffering of minor complaints, that revalued after 1 month did not show any sign of liver disease | Abdominal pain | 5 (4.6%) | Paresthesias | 3 (2.8%) | Fatigue | 2 (1.8%) | Anorexia | 1 (0.9%) | Myalgia | 1 (0.9%) | Malaise | 1 (0.9%) | Pruritus | 1 (0.9%) | Fever | 0 | Skin rash | 0 | Jaundice | 0 | Laboratory findings | | Leukocyte total count | 4250 mm3 (SD 1060) | Bilirubin | 0.75 mg dl−1 (SD 0.07) | AST | 29.5 IU−1 (SD 10.61) | ALT | 15.5 IU l−1 (SD 17.68) | Alkaline Phosphatase | 135 U l−1 (SD 63.64) | GGT | 28 U l−1 (SD 7.07) | Albumin | 3.75 g dl−1 (SD 0.49) | INR | 1 (SD 0.14) |
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