The Herb Medicine Formula “Chong Lou Fu Fang” Increases the Cytotoxicity of Chemotherapeutic Agents and Down-Regulates the Expression of Chemotherapeutic Agent Resistance-Related Genes in Human Gastric Cancer Cells In Vitro

Figure 3

Combination index values with the treatment schedule chemotherapeutic agents preceding CLFF in SGC-7901 (a–c) and BGC-823 (d–f) cells. Cells were pretreated with every chemotherapeutic agent for 24 h, followed by CLFF at fixed ratios for 48 h at 37^∘C in 5% CO₂. Data point, means of at least three independent experiment; bars, SD; (a, d) CLFF plus 5-fluorouracil; (b, e) CLFF plus oxaliplatin; (c, f) CLFF plus docetaxel. CI < 1, =1 and >1 indicate synergism, addition and antagonism, respectively.

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