Original Article

The Herb Medicine Formula “Chong Lou Fu Fang” Increases the Cytotoxicity of Chemotherapeutic Agents and Down-Regulates the Expression of Chemotherapeutic Agent Resistance-Related Genes in Human Gastric Cancer Cells In Vitro

Figure 4

CLFF treatment increase chemotherapeutic agent-induced apoptosis in SGC-7901 (a–h) and BGC-823 (i–p) cells. (a, i) both cell lines were treated without drug. (b, j) both cell lines were treated with CLFF alone. (c, k) both cell lines were treated with 5-fluorouracil alone. (d, l) both cell lines were treated with CLFF combination with 5-fluorouracil. (e, m) both cell lines were treated with oxaliplatin alone. (f, n) both cell lines were treated with CLFF combination with oxaliplatin. (g, o) both cell lines were treated with docetaxel alone. (h, p) both cell lines were treated with CLFF combination with docetaxel. Early apoptotic cells were defined as Annexin-V-positive, PI-negative cells, late apoptotic cells were defined as Annexin-V-positive, PI-positive cells.
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