The Herb Medicine Formula “Chong Lou Fu Fang” Increases the Cytotoxicity of Chemotherapeutic Agents and Down-Regulates the Expression of Chemotherapeutic Agent Resistance-Related Genes in Human Gastric Cancer Cells In Vitro
Figure 4
CLFF treatment
increase chemotherapeutic agent-induced apoptosis
in SGC-7901 (a–h) and BGC-823 (i–p)
cells. (a, i) both cell lines were treated without drug. (b, j) both
cell lines were treated with CLFF alone. (c, k) both cell lines were
treated with 5-fluorouracil alone. (d, l) both cell lines were treated
with CLFF combination with 5-fluorouracil. (e, m) both cell lines were
treated with oxaliplatin alone. (f, n) both cell lines were treated with
CLFF combination with oxaliplatin. (g, o) both cell lines were treated with
docetaxel alone. (h, p) both cell lines were treated with CLFF combination with
docetaxel. Early apoptotic cells were defined as Annexin-V-positive, PI-negative
cells, late apoptotic cells were defined as Annexin-V-positive, PI-positive cells.