Cognitive-Enhancing Effects of Polygalasaponin Hydrolysate in Aβ_25–35-Induced Amnesic Mice

Figure 4

Effect of HPS on the acquisition of spatial reference memory in MWM task on amnesic mice induced by intra-hippocampus Aβ _25–35 microinjection. Training trials were carried out on day 9 after treatments. (a) Escape latency, (b) mean speed, and (c) escape rate of mice to the hidden platform across the 3 days of training trials (4 trials per day). Gal 3 mg/kg represents galantamine 3 mg/kg group. Values represent mean ± S.E.M, 𝑛=8-10 in each group. ^#𝑃<.05, ^##𝑃<.01 compared with sham-operation group; ^∗𝑃<.05, ^∗∗𝑃<.01 compared with model group.

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