Research Article

15,16-Dihydrotanshinone I, a Compound of Salvia miltiorrhiza Bunge, Induces Apoptosis through Inducing Endoplasmic Reticular Stress in Human Prostate Carcinoma Cells

Figure 5

Effects of DHTS on the accumulation of polyubiquitinated proteins and HIF-1α protein in human prostate carcinoma cells. DU145 cells were treated with 1.5 μg/mL DHTS for the indicated time periods, and total cellular protein was subjected to Western blotting to detect the expression of ubiquitinated proteins and HIF-1α.
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