Effects of Vitamin D Plus Calcium Supplements on Pharmacokinetics of Isoflavones in Thai Postmenopausal Women

<table>Mean plasma genistein concentration-time curves after receiving three different regimens obtained from subjects who completed the study without protocol deviation (<svg height="11.125" id="M12" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 44.400002 11.125" width="44.400002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>). Each point on the curves represents mean plasma concentration at the corresponding time point. <i>Single ISO</i>: a single dose of Flava soy; <i>Single ISO + D<sub>3</sub>-calcium</i>: a single dose Flava soy and Caltrate 600 + D; <i>Continuous D<sub>3</sub>-calcium/single ISO</i>: 1 tablet of Caltrate 600 + D twice a day for 7 days, followed by a single dose of Flava soy on the 8th day.</table>

Evidence-Based Complementary and Alternative Medicine

fig3

Figure 3

Figure 3: Effects of Vitamin D Plus Calcium Supplements on Pharmacokinetics of Isoflavones in Thai Postmenopausal Women 