Original Article

A Preclinical Evaluation of Antrodia camphorata Alcohol Extracts in the Treatment of Non-Small Cell Lung Cancer Using Non-Invasive Molecular Imaging

Figure 1

ACAE treatment inhibited the proliferation of H441GL cells. (a) ACAE treatment inhibited H441GL cell growth in a dose-dependent manner but not in CGL1 control cells. ACAE-treated H441GL cells exhibited an abnormal and elongated morphology, while the CGL1 cells remained a normal physiological appearance even at the highest employed concentration of 150 μg mL-1. ACAE-mediated anti-proliferative effect was further demonstrated quantitatively by the cell number (b), MTT survival ratio (c) and colony forming efficiency ratio (d) in both H441GL and CGL1 cells. All assays were performed in triplicates and the results were shown as mean ± SD.
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(a)
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(b)
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(c)
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(d)