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Evidence-Based Complementary and Alternative Medicine
Volume 2011, Article ID 915240, 8 pages
http://dx.doi.org/10.1093/ecam/nep237
Original Article

Cassia auriculata: Aspects of Safety Pharmacology and Drug Interaction

1Interdisciplinary School of Health Sciences, University of Pune, Pune 411007, India
2University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
3National Center for Cell Sciences, Pune, India
4Applied Biotech, Vile Parle, Mumbai, India
5National Toxicology Center, Pune, India
6ICMR—Advanced Centre of Reverse Pharmacology, MRC-KHS, Vile Parle, Mumbai, India
7Manipal Education, Bangalore 560008, India

Received 8 April 2009; Accepted 12 December 2009

Copyright © 2011 Amrutesh S. Puranik et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. E. L. Cooper, “eCAM: clinical analyses and increasing visibility,” Evidence-Based Complementary and Alternative Medicine, vol. 6, no. 1, pp. 1–2, 2009. View at Publisher · View at Google Scholar · View at PubMed
  2. B. Patwardhan, A. D. B. Vaidya, and M. Chorghade, “Ayurveda and natural products drug discovery,” Current Science, vol. 86, no. 6, pp. 789–799, 2004. View at Google Scholar
  3. B. Patwardhan and R. A. Mashelkar, “Traditional medicine-inspired approaches to drug discovery: can Ayurveda show the way forward?” Drug Discovery Today, vol. 14, no. 15-16, pp. 804–811, 2009. View at Publisher · View at Google Scholar · View at PubMed
  4. S. L. Badole, N. M. Patel, P. A. Thakurdesai, and S. L. Bodhankar, “Interaction of aqueous extract of pleurotus pulmonarius (Fr.) Quel-Champ. with glyburide in alloxan induced diabetic mice,” Evidence-Based Complementary and Alternative Medicine, vol. 5, no. 2, pp. 159–164, 2008. View at Publisher · View at Google Scholar · View at PubMed
  5. A. Dasgupta, M. Hovanetz, M. Olsen, A. Wells, and J. K. Actor, “Drug-herb interaction: effect of St John's wort on bioavailability and metabolism of procainamide in mice,” Archives of Pathology and Laboratory Medicine, vol. 131, no. 7, pp. 1094–1098, 2007. View at Google Scholar
  6. G. Calapai and A. P. Caputi, “Herbal medicines: can we do without pharmacologist?” Evidence-Based Complementary and Alternative Medicine, vol. 4, no. 1, pp. 41–43, 2007. View at Publisher · View at Google Scholar · View at PubMed
  7. X.-X. Yang, Z.-P. Hu, W. Duan, Y.-Z. Zhu, and S.-F. Zhou, “Drug-herb interactions: eliminating toxicity with hard drug design,” Current Pharmaceutical Design, vol. 12, no. 35, pp. 4649–4664, 2006. View at Publisher · View at Google Scholar
  8. G. Valli and E.-G. V. Giardina, “Benefits, adverse effects and drug interactions of herbal therapies with cardiovascular effects,” Journal of the American College of Cardiology, vol. 39, no. 7, pp. 1083–1095, 2002. View at Publisher · View at Google Scholar
  9. P. Goldman, “Herbal medicines today and the roots of modern pharmacology,” Annals of Internal Medicine, vol. 135, no. 8, pp. 594–600, 2001. View at Google Scholar
  10. M. K. Pugsley, S. Authier, and M. J. Curtis, “Principles of safety pharmacology,” British Journal of Pharmacology, vol. 154, no. 7, pp. 1382–1399, 2008. View at Publisher · View at Google Scholar · View at PubMed
  11. J.-P. Valentin and T. Hammond, “Safety and secondary pharmacology: successes, threats, challenges and opportunities,” Journal of Pharmacological and Toxicological Methods, vol. 58, no. 2, pp. 77–87, 2008. View at Publisher · View at Google Scholar · View at PubMed
  12. V. Gogte, “Medicinal plants,” in Ayurvedic Pharmacology and Therapeutic Uses of Medicinal Plants (Dravyagunavignyan), S. Ramakrishnan, Ed., p. 840, Bhartiya Vidya Bhavan, Mumbai, India, 2000. View at Google Scholar
  13. M. Latha and L. Pari, “Antihyperglycaemic effect of Cassia auriculata in experimental diabetes and its effects on key metabolic enzymes involved in carbohydrate metabolism,” Clinical and Experimental Pharmacology and Physiology, vol. 30, no. 1-2, pp. 38–43, 2003. View at Publisher · View at Google Scholar
  14. S. Gupta, S. B. Sharma, S. K. Bansal, and K. M. Prabhu, “Antihyperglycemic and hypolipidemic activity of aqueous extract of Cassia auriculata L. leaves in experimental diabetes,” Journal of Ethnopharmacology, vol. 123, no. 3, pp. 499–503, 2009. View at Publisher · View at Google Scholar · View at PubMed
  15. K. J. M. Abesundara, T. Matsui, and K. Matsumoto, “α-glucosidase inhibitory activity of some Sri Lanka plant extracts, one of which, Cassia auriculata, exerts a strong antihyperglycemic effect in rats comparable to the therapeutic drug acarbose,” Journal of Agricultural and Food Chemistry, vol. 52, no. 9, pp. 2541–2545, 2004. View at Publisher · View at Google Scholar · View at PubMed
  16. M. Latha and L. Pari, “Preventive effects of Cassia auriculata L. flowers on brain lipid peroxidation in rats treated with stretozocin,” Molecular and Cellular Biochemistry, vol. 243, no. 1-2, pp. 23–28, 2003. View at Publisher · View at Google Scholar
  17. P. S. Babu and P. S. M. Prince, “Antihyperglycaemic and antioxidant effect of hyponidd, an ayurvedic herbomineral formulation in streptozotocin-induced diabetic rats,” Journal of Pharmacy and Pharmacology, vol. 56, no. 11, pp. 1435–1442, 2004. View at Publisher · View at Google Scholar · View at PubMed
  18. R. Paris and B. Cubukcu, “Presence of leucoanthocyanic chromogens in Cassia auriculata and C. goratensis Fres., adulteration of official sennas,” Annales Pharmaceutiques Françaises, vol. 20, pp. 583–587, 1962. View at Google Scholar
  19. A. Chafer, M. C. Pascual-Martí, A. Salvador, and A. Berna, “Supercritical fluid extraction and HPLC determination of relevant polyphenolic compounds in grape skin,” Journal of Separation Science, vol. 28, no. 16, pp. 2050–2056, 2005. View at Publisher · View at Google Scholar
  20. G.-Q. He, H.-P. Xiong, Q.-H. Chen, H. Ruan, Z.-Y. Wang, and L. Traoré, “Optimization of conditions for supercritical fluid extraction of flavonoids from hops (Humulus lupulus L.),” Journal of Zhejiang University Science B, vol. 6, no. 10, pp. 999–1004, 2005. View at Publisher · View at Google Scholar · View at PubMed
  21. C. Yang, Y.-R. Xu, and W.-X. Yao, “Extraction of pharmaceutical components from Ginkgo biloba leaves using supercritical carbon dioxide,” Journal of Agricultural and Food Chemistry, vol. 50, no. 4, pp. 846–849, 2002. View at Publisher · View at Google Scholar
  22. C. D. Stalikas, “Extraction, separation, and detection methods for phenolic acids and flavonoids,” Journal of Separation Science, vol. 30, no. 18, pp. 3268–3295, 2007. View at Publisher · View at Google Scholar · View at PubMed
  23. O. Sticher, “Natural product isolation,” Natural Product Reports, vol. 25, no. 3, pp. 517–554, 2008. View at Publisher · View at Google Scholar · View at PubMed
  24. Q. Lang and C. M. Wai, “Supercritical fluid extraction in herbal and natural product studies—a practical review,” Talanta, vol. 53, no. 4, pp. 771–782, 2001. View at Publisher · View at Google Scholar
  25. E. A. Ryan, M. E. Pick, and C. Marceau, “Use of alternative medicines in diabetes mellitus,” Diabetic Medicine, vol. 18, no. 3, pp. 242–245, 2001. View at Publisher · View at Google Scholar
  26. “Office of training and communications DoDIH-center for drug evaluation and research (CDER), food and drug administration,” in Guidance for Industry—Diabetes Mellitus: Developing Drugs and Therapeutic Biologics for Treatment and Prevention, Services USDoHaH, Ed., p. 34, Rockville, Md, USA, 2008.
  27. Z. Wang, M. Ashraf-Khorassani, and L. T. Taylor, “Feasibility study of online supercritical fluid extraction-liquid chromatography-UV absorbance-mass spectrometry for the determination of proanthocyanidins in grape seeds,” Journal of Chromatographic Science, vol. 43, no. 3, pp. 109–115, 2005. View at Google Scholar
  28. Y. Ogasawara, Y. Mukai, T. Togawa, T. Suzuki, S. Tanabe, and K. Ishii, “Determination of plasma thiol bound to albumin using affinity chromatography and high-performance liquid chromatography with fluorescence detection: ratio of cysteinyl albumin as a possible biomarker of oxidative stress,” Journal of Chromatography B, vol. 845, no. 1, pp. 157–163, 2007. View at Publisher · View at Google Scholar · View at PubMed
  29. M. C. Whittle, J. F. Stobaugh, and O. S. Wong, “High performance liquid chromatographic method for the determination of homocysteine in human plasma using a water-soluble phosphine reducing agent and fluorogenic derivatization,” Chromatographia, vol. 52, pp. S78–S82, 2000. View at Google Scholar
  30. J. Kajstura, F. Fiordaliso, A. M. Andreoli et al., “IGF-1 overexpression inhibits the development of diabetic cardiomyopathy and angiotensin II-mediated oxidative stress,” Diabetes, vol. 50, no. 6, pp. 1414–1424, 2001. View at Google Scholar
  31. D. Stepensky, M. Friedman, I. Raz, and A. Hoffman, “Pharmacokinetic-pharmacodynamic analysis of the glucose-lowering effect of metformin in diabetic rats reveals first-pass pharmacodynamic effect,” Drug Metabolism and Disposition, vol. 30, no. 8, pp. 861–868, 2002. View at Publisher · View at Google Scholar
  32. B. Patwardhan, “Ethnopharmacology and drug discovery,” Journal of Ethnopharmacology, vol. 100, no. 1-2, pp. 50–52, 2005. View at Publisher · View at Google Scholar · View at PubMed
  33. E. L. Cooper, “eCAM: an emerging linkage with ethnopharmacology?” Evidence-Based Complementary and Alternative Medicine, vol. 5, no. 4, pp. 365–366, 2008. View at Publisher · View at Google Scholar · View at PubMed
  34. B. Patwardhan, “Ayurveda: the 'Designer' medicine: a review of ethnopharmacology and bioprospecting research,” Indian Drugs, vol. 37, no. 5, pp. 213–227, 2000. View at Google Scholar
  35. B. M. Schmidt, D. M. Ribnicky, P. E. Lipsky, and I. Raskin, “Revisiting the ancient concept of botanical therapeutics,” Nature Chemical Biology, vol. 3, no. 7, pp. 360–366, 2007. View at Publisher · View at Google Scholar · View at PubMed
  36. J. R. Senior, “Monitoring for hepatotoxicity: what is the predictive value of liver "function" tests?” Clinical Pharmacology and Therapeutics, vol. 85, no. 3, pp. 331–334, 2009. View at Publisher · View at Google Scholar · View at PubMed
  37. L. Pari and M. Latha, “Effect of Cassia auriculata flowers on blood sugar levels, serum and tissue lipids in streptozotocin diabetic rats,” Singapore Medical Journal, vol. 43, no. 12, pp. 617–621, 2002. View at Google Scholar
  38. M. C. Sabu and T. Subburaju, “Effect of Cassia auriculata Linn. on serum glucose level, glucose utilization by isolated rat hemidiaphragm,” Journal of Ethnopharmacology, vol. 80, no. 2-3, pp. 203–206, 2002. View at Publisher · View at Google Scholar
  39. L. Babuin and A. S. Jaffe, “Troponin: the biomarker of choice for the detection of cardiac injury,” Canadian Medical Association Journal, vol. 173, no. 10, pp. 1191–1202, 2005. View at Publisher · View at Google Scholar · View at PubMed
  40. M. Helm, J. Hauke, A. Weiss, and L. Lampl, “Cardiac troponin T as a biochemical marker of myocardial injury early after trauma. Diagnostic value of a qualitative bedside test,” Chirurg, vol. 70, no. 11, pp. 1347–1352, 1999. View at Google Scholar
  41. J. Joseph, L. Joseph, S. Devi, and R. H. Kennedy, “Effect of anti-oxidant treatment on hyperhomocysteinemia-induced myocardial fibrosis and diastolic dysfunction,” Journal of Heart and Lung Transplantation, vol. 27, no. 11, pp. 1237–1241, 2008. View at Publisher · View at Google Scholar · View at PubMed
  42. J. Kennedy, “Herb and supplement use in the US adult population,” Clinical Therapeutics, vol. 27, no. 11, pp. 1847–1858, 2005. View at Publisher · View at Google Scholar · View at PubMed