Original Article
Cassia auriculata: Aspects of Safety Pharmacology and Drug Interaction
Table 2
Ventricular pressures of CA-dosed animals.
| | Control (0.5% NaCMC) | C. auriculata (mg kg-1) | | Ventricular pressures (mmHg) | HA | SFE | | 500 | 1000 | 250 | 500 | 1000 |
| | Male | | | | | | | | Systolic blood pressure | 124.2 6.2 | 119.4 9.6 | 117.2 4.7 | 121.3 8.1 | 113.1 11.2 | 121.9 3.2 | | Diastolic blood pressure | 83.2 4.3 | 81.0 3.4 | 79.5 4.0 | 82.1 4.8 | 79.2 7.01 | 81.9 6.4 | | Female | | | | | | | | Systolic blood pressure | 119.3 8.21 | 116.2 3.9 | 118.7 3.8 | 120.1 11.5 | 116.9 9.21 | 118.3 9.8 | | Diastolic blood pressure | 78.3 6.2 | 77.3 4.1 | 81.8 2.9 | 79.9 3.9 | 81.2 4.01 | 77.4 8.3 |
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Data are expressed as mean SD, n = 6. No significant difference ventricular pressures seen at increasing doses of both CA-HA and CA-SFE.
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