The Budding Yeast “<i>Saccharomyces cerevisiae</i>” as a Drug Discovery Tool to Identify Plant-Derived Natural Products with Anti-Proliferative Properties

<table>Growth of wild-type (OD 600 nm) as a function of time. Wild-type cells were diluted from an overnight culture to an OD600 of <i>~</i>0.01 and allowed to grow until the OD600 reached <i>~</i>0.05, ensuring that the cells were in logarithmic phase. Drug was then added and growth rate was measured as the optical density of cells (OD600) as a function of time (h) in rich medium. All compounds were diluted in 100% DMSO, and all assays, including the “no compound” control, contained 1% DMSO. The growth in the presence of 100 <i>μ</i>g/ml of natural compound Lyc is presented.</table>

Evidence-Based Complementary and Alternative Medicine

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Figure 1

Figure 1: The Budding Yeast “<i>Saccharomyces cerevisiae</i>” as a Drug Discovery Tool to Identify Plant-Derived Natural Products with Anti-Proliferative Properties 

Figure 1 | The Budding Yeast “Saccharomyces cerevisiae” as a Drug Discovery Tool to Identify Plant-Derived Natural Products with Anti-Proliferative Properties 