Enhanced Antitumoral Activity of Extracts Derived from Cultured Udotea flabellum (Chlorophyta)

Table 1

Growth inhibition (IC₅₀) of U. flabellum extracts on cancer cell lines (𝑃≤0.001).

Cancer cells	IC50±SD (𝜇g mL^−1)
	Time = 0	Day = 10	Day = 20	Day = 30
SiHa	276.2±1.91
A		30.4±3.9	100.6±2.65	493.1±2.1
B		42.7±0.9	75.8±1.1	623.3±2.7
C		10.2±1.2	64.5±1.5	788.9±1.2
D		13.1±2.7	62.4±1.2	547.8±2.1
		𝐹(4,10)=6814	𝐹(4,10)=8113	𝐹(4,10)=24910
Docetaxel	0.32±0.01
HeLa	296.6±0.9
A		49.7±2.1	45.3±1.3	413.6±0.9
B		39.2±3.1	34.8±1.9	580.4±1.9
C		53.8±2.7	67.4±2.8	568.2±1.2
D		63.8±1.8	76.6±1.8	482.6±0.9
		𝐹(4,10)=7143	𝐹(4,10)=10350	𝐹(4,10)=27690
Docetaxel	0.20±0.04
Hep-2	52.9±1
A		16.6±1.3	71.7±2.1	98.4±1.2
B		19.1±1.8	60.3±1.8	100.7±1.8
C		16.7±0.9	75.2±1.9	91.5±2.3
D		33.5±1.4	91.1±1.9	106.1±1.6
		𝐹(4,10)=424.1	𝐹(4,10)=203.4	𝐹(4,10)=521.7
Docetaxel	0.08±0.03
KB	47.8±1.2
A		23.4±1.9	134.6±1.9	106.4±1.5
B		29.8±2.1	138.1±1.5	109.7±1.5
C		32.4±1.7	117.3±1.2	123.4±0.9
D		28.9±1.2	112.7±1.4	126.7±2.3
		𝐹(4,10)=113.9	𝐹(4,10)=1854	𝐹(4,10)=1269
Docetaxel	0.23±0.07

IC₅₀: half maximal (50%) inhibitory concentration (IC) of organic extracts.