Efficacy of Brazilian Propolis against Herpes Simplex Virus Type 1 Infection in Mice and Their Modes of Antiherpetic Efficacies

Table 2

Effect of propolis extracts on virus titers in skin and brain of HSV-1-infected mice.

Administration	Virus titer (log10 PFU/organ)
	Skin	Brain
Control	6.1±0.07	2.2±0.02
AF-06	6.3±0.11	1.6±0.48
AF-07	5.7±0.09^∗	<1.0±0.00^∗∗
AF-08	6.1±0.04	<1.0±0.00^∗∗
ACV (5 mg/kg)	5.4±0.14^∗	<1.0±0.00^∗∗

Values are mean ± standard error of the mean (SEM) of five mice.
^∗𝑃<.01 and ^∗∗𝑃<.001 versus control by Student’s 𝑡-test.