KIOM-4 Protects against Oxidative Stress-Induced Mitochondrial Damage in Pancreatic β-cells via Its Antioxidant Effects
Figure 1
The effect of KIOM-4 on cell-free generation of superoxide and hydroxyl radicals. (a) Superoxide radicals were generated by xanthine/xanthine oxidase and reacted with DMPO; the resultant DMPO-OOH adducts were detected using an ESR spectrometer. (b) Hydroxyl radicals were generated by the Fenton reaction (H2O2/FeSO4) and reacted with DMPO; the resultant DMPO-OH adducts were detected using an ESR spectrometer.
