Anti-Cancer Effects of Protein Extracts from Calvatia lilacina, Pleurotus ostreatus and Volvariella volvacea
Figure 7
Evaluation of the critical mechanism in PO and VV protein extract-induced apoptosis. (a) The SW480 cells were treated with (a) PO and (b) VV protein extracts (0 (untreated) or 10 g mL−1) for 24 h, pretreated with 10 mM NAC, 10 mM GSH or 5 M CyA for 1 h, followed by (a) PO and (b) VV protein extracts (10 g mL−1) treatment for 24 h, and then analyzed for DNA damage. Data in each panel show the percentages of cells in the SubG1 (DNA-damaged cells), G1, S and G2/M phases of cell cycle. These experiments were performed at least three times and a representative experiment is presented.
