Participation of JNK, ROS and caspases in cordycepin-induced apoptosis. MA-10 cells were incubated with or without 100 μM cordycepin in the presence or absence of 1 μM JNK inhibitor (SP600125 which abbreviated as SP) and 1 mM ROS inhibitor (NAC) (a), or 100 μM caspases inhibitor (b), respectively, for 24 h, and the change of cell cycle in percentage of subG1 phase was analyzed and illustrated. Data represent the mean ± SEM of three separate experiments. *Groups differing significantly from control (). #Groups differing significantly from 100 μM cordycepin treatment.
