Research Article
Action of Coriandrum sativum L. Essential Oil upon Oral Candida albicans Biofilm Formation
Table 1
Anti-Candida activity (MIC-mg/mL) of the essential oils, the dichloromethane (DE) and hexane (HE) extracts from the medicinal species studied.
| | Candida spp. | A. tuberosum | C. sativum | C. martinii | C. winterianus | S. chamaecyparissus | | EO | DE | EO | HE | EO | DE | EO | DE | EO | DE |
| | Culture collection | | | | | | | | | | | | C. albicans CBS 562 | 0.500 | 0.500 | 0.015 | 0.125 | 0.063 | 0.250 | 1.000 | 0.125 | 1.000 | 0.250 | | C. krusei CBS 573 | >1.0 | >1.0 | 0.015 | 0.125 | 0.063 | 0.125 | 0.063 | 0.063 | 0.500 | 0.500 | | C. parapsilosis CBS 604 | 0.015 | 0.015 | 0.125 | 0.031 | 0.125 | 0.063 | 1.000 | 0.125 | 1.000 | 1.000 | | C. dubliniensis CBS 7987 | 1.000 | >1.0 | 0.007 | 0.031 | 0.125 | 0.250 | 0.500 | 0.125 | 0.063 | 0.063 | | C. tropicalis CBS 94 | >1.0 | >1.0 | 0.125 | 0.500 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 |
| | Clinical isolatesa | | | | | | | | | | | | C. albicans 3 A5 | 0.500 | >1.0 | 0.015 | 1.000 | 0.250 | 1.000 | 1.000 | 1.000 | 1.000 | >1.0 | | C. albicans 13 A5 | 0.500 | >1.0 | 0.031 | 1.000 | 0.063 | 1.000 | 0.500 | 1.000 | 1.000 | >1.0 | | C. albicans 41 M2 | 0.500 | >1.0 | 0.031 | 1.000 | 0.063 | 1.000 | 1.000 | 1.000 | 1.000 | >1.0 | | C. albicans 50 M2 | 0.500 | >1.0 | 0.063 | 1.000 | 0.250 | 1.000 | 0.500 | 1.000 | 1.000 | >1.0 | | C. krusei 56 M3 | 0.007 | >1.0 | 0.007 | 0.031 | 0.007 | 0.063 | 0.031 | 0.002 | 0.125 | 0.063 | | C. krusei 56 M4 | 1.000 | >1.0 | 0.007 | 0.015 | 0.007 | 0.007 | 0.007 | 0.007 | 0.007 | 0.500 | | C. krusei 56 M6 | 1.000 | >1.0 | 0.007 | 0.002 | 0.007 | 0.007 | 0.007 | 0.007 | 0.007 | 0.015 | | C. parapsilosis 45 M2 | 0.015 | >1.0 | 0.007 | 0.063 | 0.031 | 0.063 | 0.250 | 0.250 | 0.500 | 0.125 | | C. parapsilosis 45 M4 | 0.015 | >1.0 | 0.007 | 0.125 | 0.015 | 0.031 | 0.063 | 0.063 | 0.250 | 0.125 | | C. parapsilosis 45 M5 | 0.015 | >1.0 | 0.015 | 0.007 | 0.250 | 1.000 | 1.000 | 0.063 | 1.000 | 1.000 | | C. dubliniensis 26 A2 | 1.000 | >1.0 | 0.063 | 0.250 | 0.250 | 0.500 | 1.000 | 0.500 | 0.500 | 0.500 | | C. dubliniensis 26 A3 | 1.000 | >1.0 | 0.031 | 0.250 | 0.250 | 0.500 | 1.000 | 0.250 | 0.250 | 0.500 | | C. dubliniensis 26 A4 | >1.0 | >1.0 | 0.500 | 0.250 | 1.000 | 0.250 | 1.000 | 0.250 | 0.500 | 1.000 | | C. tropicalis 53 M6 | >1.0 | >1.0 | 0.125 | 0.500 | >1.0 | >1.0 | >1.0 | >1.0 | 1.000 | 1.000 | | C. tropicalis 53 M7 | >1.0 | >1.0 | 0.063 | 0.250 | 0.250 | 0.250 | 1.000 | 1.000 | >1.0 | >1.0 | | C. tropicalis 53 M8 | >1.0 | >1.0 | 0.031 | 0.250 | >1.0 | >1.0 | >1.0 | >1.0 | >1.0 | >1.0 |
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aThe codes correspond to the number of the volunteers and the place of sample origin; (A)-periodontal pocket; (M) oral mucosa.
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