Inhibitory Effect of Polyphenol-Rich Fraction from the Bark of Acacia mearnsii on Itching Associated with Allergic Dermatitis

Figure 6

mRNA expression levels of serine palmitoyl transferase (a) and ceramidase (b) in the skin. HR-1 mice were given free access to a normal diet (control group), HR-AD diet (AD group), HR-AD diet with 1.5% PrA, or HR-AD diet with 3.0% PrA for 6 weeks. After 6 weeks, the skin was harvested, and serine palmitoyl transferase (a) and ceramidase (b) mRNA expression levels were measured using real-time RT-PCR. GAPDH was used as a housekeeping gene. mRNA expression levels are presented as the percentage of the control group (100%). Data represent the mean ± SD for 8 mice. Tukey’s test: *𝑃<0.05 versus control group, ^#𝑃<0.05 and ^##𝑃<0.01 versus AD group.

(a)

(b)